Manuel Mueller King's College London

Research in our lab focuses on using synthetic protein chemistry to elucidate how proteins are controlled by post-translational modifications. We are particularly interested in modifications of the polypeptide backbone, and how such processes are involved in molecular ageing.


We are located in the recently formed chemistry department at King's College London. Our research is generously funded by a Sir Henry Dale Fellowship, jointly provided by the Wellcome Trust and the Royal Society.

Lab News:


2021 May


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2020 Oct

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2019 December


2019 November

2019 September

2019 June


2018 September


2018 August


2017 October

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2017 June

2017 June

2017 May

2017 February

2017 January


Sofia and Karola's paper on 'designer' p53 is published in Chemical Science (

Karola receives a Poster Prize at the RSC Chemical Biology Symposium - congratulations!

Niyaz Zaman - LIDo rotation student - joins the lab

Dr Greg Hughes - Postdoc - joins the lab

Karola successfully defended her thesis. Congratulations Dr Gerecht!


Matt Hess - LIDo iCASE PhD Student - joins the lab

Yasmin Gariba-Hamilton - King's MSci student - joins the lab


Tianze's paper on an autocatalytic protein backbone modification is published in Biochemistry. Great collaboration with the Politis lab at KCL (


Olga Tereszkowska-Kaminska - King's undergraduate student - joins the lab for a (remote) summer project


Jasmine's review on viral anticancer proteins is published in Cancers


Karola wins the 2019 Daniell Prize from KCL Chemistry (jointly with Magd Badaoui & Grant Pellowe). Congratulations!

Jonathan Davies - PhD Student - joins the lab


Florence Stoffel - King's Undergraduate Research Fellow - joins the lab


Rachelle Benarroch - King's MSci student - returns to the lab


Book chapter on 'Chemical Protein Synthesis: Strategies and Biological Applications' published in 'Chemical and Biological Synthesis: Enabling Approaches for Understanding Biology' (Editors: Nick J Westwood, Adam Nelson)

Perspective on Post-Translational Modifications of Protein Backbones published in special issue of Biochemistry 'The Future of Biochemistry'

Jasmine Wyatt - PhD Student (Jointly with Tavassoli Lab @ KCL, BRC) - joins the lab

Tianze Zhang - PhD Student (CSC) - joins the lab


Halime Karakoy - King's MSci Student - joins the lab


Rachelle Benarroch - King's Undergraduate Research Fellow - joins the lab for a summer project


Daynea Wallock-Richards - Postdoc in Chemical Biology - joins the lab

George Preston - Visiting Postdoc from KCL Environmental Carcinogenesis - joins the lab

Karola Gerecht - PhD Student (LIDo) - joins the lab

Sofia Margiola - PhD Student - joins the lab