Research in our lab focuses on using synthetic protein chemistry to elucidate how proteins are controlled by post-translational modifications. We are particularly interested in modifications of the polypeptide backbone, and how such processes are involved in molecular ageing.
We are located in the recently formed chemistry department at King's College London. Our research is generously funded by a Sir Henry Dale Fellowship, jointly provided by the Wellcome Trust and the Royal Society.
Sofia and Karola's paper on 'designer' p53 is published in Chemical Science (https://doi.org/10.1039/D1SC00396H)
Karola receives a Poster Prize at the RSC Chemical Biology Symposium - congratulations!
Niyaz Zaman - LIDo rotation student - joins the lab
Dr Greg Hughes - Postdoc - joins the lab
Karola successfully defended her thesis. Congratulations Dr Gerecht!
Matt Hess - LIDo iCASE PhD Student - joins the lab
Yasmin Gariba-Hamilton - King's MSci student - joins the lab
Tianze's paper on an autocatalytic protein backbone modification is published in Biochemistry. Great collaboration with the Politis lab at KCL (https://pubs.acs.org/doi/10.1021/acs.biochem.0c00502)
Olga Tereszkowska-Kaminska - King's undergraduate student - joins the lab for a (remote) summer project
Jasmine's review on viral anticancer proteins is published in Cancers
Karola wins the 2019 Daniell Prize from KCL Chemistry (jointly with Magd Badaoui & Grant Pellowe). Congratulations!
Jonathan Davies - PhD Student - joins the lab
Florence Stoffel - King's Undergraduate Research Fellow - joins the lab
Rachelle Benarroch - King's MSci student - returns to the lab
Book chapter on 'Chemical Protein Synthesis: Strategies and Biological Applications' published in 'Chemical and Biological Synthesis: Enabling Approaches for Understanding Biology' (Editors: Nick J Westwood, Adam Nelson)
Perspective on Post-Translational Modifications of Protein Backbones published in special issue of Biochemistry 'The Future of Biochemistry'
Jasmine Wyatt - PhD Student (Jointly with Tavassoli Lab @ KCL, BRC) - joins the lab
Tianze Zhang - PhD Student (CSC) - joins the lab
Halime Karakoy - King's MSci Student - joins the lab
Rachelle Benarroch - King's Undergraduate Research Fellow - joins the lab for a summer project
Daynea Wallock-Richards - Postdoc in Chemical Biology - joins the lab
George Preston - Visiting Postdoc from KCL Environmental Carcinogenesis - joins the lab
Karola Gerecht - PhD Student (LIDo) - joins the lab
Sofia Margiola - PhD Student - joins the lab